Product guide · Food supplement
GN Laboratories 110 Fahrenheit – Advanced Fat Burner & Muscle Support
Capsule formula with stimulants from GN Laboratories. This guide sets out what the manufacturer states about the composition of GN Laboratories 110 Fahrenheit, what independent research says about its main ingredients, and the safety and regulatory points that apply.
Back to the product- Named ingredients
- 8
- Amounts stated
- None
- Status
- Food supplement
- Evidence summaries
- 5
Overview
Manufacturer information110 Fahrenheit combines cayenne pepper, bitter orange, L-carnitine, citrus bergamot, ProGBB™ and wakame extract with lion's mane and cocoa extract.
Ingredients & composition
Manufacturer information| Ingredient | Amount |
|---|---|
| Cayenne pepper | Not stated |
| Bitter orange | Not stated |
| L-carnitine | Not stated |
| Citrus bergamot | Not stated |
| ProGBB™ | Not stated |
| Wakame extract | Not stated |
| Lion's mane | Not stated |
| Cocoa extract | Not stated |
The manufacturer does not state the amount of any ingredient. Without amounts, the research summarised in this guide cannot be related to this product's dose.
Not covered in detail in this guide: ProGBB™, Wakame extract, Cocoa extract.
Scientific background
Independent researchCapsaicin (cayenne pepper, capsinoids)
Capsaicin is the pungent compound in chilli and cayenne pepper; capsinoids are milder relatives.
Synephrine (bitter orange, Citrus aurantium)
p-Synephrine is the main protoalkaloid of bitter orange (Citrus aurantium). It is structurally related to adrenaline and is used in weight-loss and pre-workout products1.
L-carnitine (Carnipure®, ALCAR)
L-carnitine transports fatty acids into mitochondria for energy production. The body makes it, and it is found in meat. Acetyl-L-carnitine (ALCAR) is a related form.
Bergamot polyphenols
Bergamot (Citrus bergamia) fruit extracts contain flavonoids studied for blood lipids.
Lion's mane (Hericium erinaceus)
Lion's mane (Hericium erinaceus) is an edible mushroom studied for compounds that may influence nerve growth factors.
Research evidence
Independent researchCapsaicin (cayenne pepper, capsinoids)
A meta-analysis in healthy adults found moderate increases in resting metabolic rate and fat oxidation with capsaicinoids or capsinoids, and called for higher-quality studies2.
Synephrine (bitter orange, Citrus aurantium)
A review of human clinical studies reported small increases in energy expenditure and modest weight loss with bitter orange extract or p-synephrine products over 6–12 weeks, many in combination with other ingredients1.
L-carnitine (Carnipure®, ALCAR)
A meta-analysis in healthy people found that L-carnitine supplementation may improve some measures of physical performance, but concluded that more robust trials are needed to determine the best dose3.
Bergamot polyphenols
A network meta-analysis of nutraceuticals found bergamot among the most effective for lowering LDL and total cholesterol, but noted that the evidence came from relatively small study groups4.
Lion's mane (Hericium erinaceus)
A small pilot study in healthy adults found lion's mane safe and well tolerated, with small-to-moderate effects on cognitive function that warrant larger trials5.
Evidence limitations
Independent researchThis product does not state all ingredient amounts, so the doses used in research cannot be compared with what one serving provides.
The studies summarised in this guide examined single ingredients. No published study has tested this product or this combination of ingredients.
Capsaicin (cayenne pepper, capsinoids)
Effects are small and the studies are heterogeneous2.
Synephrine (bitter orange, Citrus aurantium)
Most studies are small, short and use multi-ingredient products, and longer studies are needed to establish efficacy and safety1.
L-carnitine (Carnipure®, ALCAR)
The trials are heterogeneous3.
Bergamot polyphenols
Studies are few and small4.
Lion's mane (Hericium erinaceus)
The human evidence is from small pilot studies5.
Safety & potential risks
- Do not exceed the recommended daily dose.
- Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
- Keep out of the reach of young children.
- Contains stimulants. Not recommended for children, or for pregnant or breastfeeding women.
Capsaicin (cayenne pepper, capsinoids)
Can cause stomach irritation and heartburn.
Synephrine (bitter orange, Citrus aurantium)
The reviewed studies did not report serious adverse effects at the doses tested1, but combining synephrine with caffeine and other stimulants increases cardiovascular stress. People with high blood pressure, heart-rhythm disorders or taking stimulant or antidepressant medication should avoid it.
L-carnitine (Carnipure®, ALCAR)
Generally well tolerated; high doses can cause digestive upset and a fishy body odour.
Bergamot polyphenols
Generally well tolerated; people taking cholesterol-lowering medicines should ask a doctor first.
Lion's mane (Hericium erinaceus)
Generally well tolerated; people with mushroom allergy should avoid it5.
Regulatory status
Sold as a food supplement. No health claims are made for this product.
Capsaicin (cayenne pepper, capsinoids)
No health claim for this ingredient is authorised in the EU6; it is sold under national food-supplement rules7.
Synephrine (bitter orange, Citrus aurantium)
Bitter orange extracts are used in EU food supplements under national rules, which differ between Member States7.
L-carnitine (Carnipure®, ALCAR)
No health claim for this ingredient is authorised in the EU6; it is sold under national food-supplement rules7.
Scientific references
- Stohs SJ, Preuss HG, Shara M. A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine. Int J Med Sci. 2012;9:527-538. PubMed 22991491
- Irandoost P, Lotfi Yagin N, Namazi N, et al. The effect of capsaicinoids or capsinoids in red pepper on thermogenesis in healthy adults: a systematic review and meta-analysis. Phytother Res. 2021;35:1358-1377. PubMed 33063385
- Vecchio M, Chiaramonte R, Testa G, et al. Clinical effects of L-carnitine supplementation on physical performance in healthy subjects, the key to success in rehabilitation: a systematic review and meta-analysis. J Funct Morphol Kinesiol. 2021;6:93. PubMed 34842765
- Osadnik T, Goławski M, Lewandowski P, et al. A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Pharmacol Res. 2022;183:106402. PubMed 35988871
- Evans C, Kalman D, Goodrich J, et al. A pilot proof-of-concept study to evaluate the physiological and cognitive impacts of Hericium erinaceus on healthy adults. Nutrients. 2026;18. PubMed 42884628
- Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods. Official Journal of the European Union. Source
- Directive 2002/46/EC on the approximation of the laws of the Member States relating to food supplements. Official Journal of the European Union. Source
Sources checked against PubMed, Crossref or the official publisher on 2026-11-04. Manufacturer information is taken from the product's own data and has not been independently tested.
The product
GN Laboratories 110 Fahrenheit – Advanced Fat Burner & Muscle Support
€39,90