Product guide · Restricted substance
Smart Brothers GW-501516 (cardarine) 60 caps
Research compound from Smart Brothers, 60 capsules. This guide sets out what the manufacturer states about the composition of Smart Brothers GW-501516 (cardarine) 60 caps, what independent research says about its main ingredient, and the safety and regulatory points that apply. It contains substances that are not authorised as food or medicine in the EU. This guide is educational: it does not recommend use and gives no directions for use.
Back to the product- Named ingredients
- 1
- Amounts stated
- None
- Status
- Restricted substance
- Evidence summaries
- 1
Overview
Manufacturer informationSmart Brothers GW-501516 (cardarine) 60 caps contains GW-501516 (Cardarine). Each pack holds 60 capsules. The strength is not stated in the product data.
Ingredients & composition
Manufacturer information| Ingredient | Amount |
|---|---|
| GW-501516 (Cardarine) | Not stated |
The manufacturer does not state the amount of any ingredient. Without amounts, the research summarised in this guide cannot be related to this product's dose.
Scientific background
Independent researchGW501516 (cardarine)
GW501516 (cardarine) is a PPARδ agonist, not a SARM. It acts on a receptor that regulates fat metabolism and was investigated as a drug candidate for obesity, type 2 diabetes and blood-lipid disorders1.
Research evidence
Independent researchGW501516 (cardarine)
Early human studies examined its effects on blood lipids in people with low HDL cholesterol or metabolic syndrome2. There are no published controlled trials of GW501516 for exercise performance in humans.
Evidence limitations
Independent researchThis product does not state all ingredient amounts, so the doses used in research cannot be compared with what one serving provides.
No published study has tested this specific product; the research summarised here concerns the ingredient itself.
GW501516 (cardarine)
The human evidence consists of small, short metabolic studies. Long-term safety in humans has not been established, and the compound has not been approved as a medicine.
Safety & potential risks
Independent researchGW501516 (cardarine)
Because GW501516 never completed clinical development, its risks in humans are not adequately characterised. Products sold as research chemicals are not quality-controlled3.
Regulatory status
Contains GW-501516 (cardarine), an investigational PPARδ agonist whose clinical development was discontinued after carcinogenicity findings in animal studies. It is not authorised as a medicinal product or as food in the EU and is on the WADA Prohibited List. No dosing information for human use is provided.
Scientific references
- Pokrywka A, Cholbinski P, Kaliszewski P, et al. Metabolic modulators of the exercise response: doping control analysis of an agonist of the peroxisome proliferator-activated receptor δ (GW501516) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR). J Physiol Pharmacol. 2014;65:469-476. PubMed 25179079
- Olson EJ, Pearce GL, Jones NP, et al. Lipid effects of peroxisome proliferator-activated receptor-δ agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2012;32:2289-2294. PubMed 22814748
- Van Wagoner RM, Eichner A, Bhasin S, et al. Chemical composition and labeling of substances marketed as selective androgen receptor modulators and sold via the internet. JAMA. 2017;318:2004-2010. PubMed 29183075
- Directive 2001/83/EC on the Community code relating to medicinal products for human use. Official Journal of the European Union. Source
- Regulation (EU) 2015/2283 on novel foods. Official Journal of the European Union. Source
- World Anti-Doping Agency. The Prohibited List (current edition). Source
Sources checked against PubMed, Crossref or the official publisher on 2026-11-04. Manufacturer information is taken from the product's own data and has not been independently tested.
The product
Smart Brothers GW-501516 (cardarine) 60 caps
€39,90