Core Labs Rad 150 60 caps

RAD-150

RAD-150 (sometimes sold as TLB-150) is marketed as an esterified derivative of RAD-140. No peer-reviewed research on RAD-150 itself has been published; the information available concerns RAD-140¹.

N-acetylcysteine (NAC)

N-acetylcysteine (NAC) is a form of the amino acid cysteine and a precursor of glutathione, the body's main antioxidant. It is also used as a licensed medicine, for example as a mucolytic.

Vitamin E (α-tocopherol)

Vitamin E is a fat-soluble antioxidant. EFSA set adequate intakes of 13 mg a day for men and 11 mg a day for women, as α-tocopherol². Vitamin E TPGS is a water-soluble form used as an ingredient and absorption enhancer.

RAD-150

There are no published human or animal studies of RAD-150. For RAD-140, the only human trial was a phase 1 study in women with advanced breast cancer³.

N-acetylcysteine (NAC)

A meta-analysis found that NAC can raise glutathione levels after physical exertion, with mixed effects on other markers of oxidative stress and muscle damage⁴.

Vitamin E (α-tocopherol)

The EU authorises the claim that vitamin E contributes to the protection of cells from oxidative stress⁵. Benefits of high-dose supplements beyond meeting needs are not established.

RAD-150

Its identity, purity and effects have not been characterised in the scientific literature. Analyses of products sold online as SARMs found that many did not contain the substance or amount stated on the label, and some contained other unapproved drugs⁶.

N-acetylcysteine (NAC)

Effects on performance in healthy people are not established⁴.

Vitamin E (α-tocopherol)

Most people in the EU meet their needs from food².

RAD-150

Human safety is unknown. Liver injury has been reported with products containing RAD-140⁷. A systematic review of SARM use by athletes reports liver toxicity, heart toxicity, tendon damage, suppression of natural testosterone and other androgenic effects⁸. A national case series linked SARMs and other bodybuilding products to drug-induced liver injury⁹.

N-acetylcysteine (NAC)

NAC can cause nausea and digestive upset; people with asthma or taking nitroglycerin should ask a doctor first.

Vitamin E (α-tocopherol)

The EU Scientific Committee on Food set a tolerable upper intake level of 300 mg a day for adults¹⁰. High doses may increase bleeding risk in people taking anticoagulants.

Contains a selective androgen receptor modulator (SARM). SARMs are investigational substances that are not authorised as medicinal products or as food (including food supplements) in the EU and are on the World Anti-Doping Agency (WADA) Prohibited List. No dosing information for human use is provided.

RAD-150

RAD-150 is not an approved medicine and is not permitted in food or food supplements in the EU¹¹¹². SARMs have been on the World Anti-Doping Agency Prohibited List since 2008 and are prohibited at all times¹³¹⁴.

N-acetylcysteine (NAC)

NAC is a medicinal substance in several EU Member States; its use in food supplements depends on national rules¹¹. No health claim for this ingredient is authorised in the EU⁵; botanical ingredients are sold under national food-supplement rules¹⁵.

Vitamin E (α-tocopherol)

It is a permitted nutrient in EU food supplements¹⁵; authorised claims may only be used in their approved wording and when the product is at least a source of the nutrient⁵.