GynSyn Labs MK677 liquid 30 ml (1ml 90mg) - GIGACULT

Product guide · Restricted substance

GynSyn Labs MK677 liquid 30 ml (1ml 90mg)

GynSyn Labs

Research compound from GynSyn Labs, 30 ml of liquid. This guide sets out what the manufacturer states about the composition of GynSyn Labs MK677 liquid 30 ml (1ml 90mg), what independent research says about its main ingredient, and the safety and regulatory points that apply. It contains substances that are not authorised as food or medicine in the EU. This guide is educational: it does not recommend use and gives no directions for use.

Educational guide · Sources checked 4 November 2026 · 6 references

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Named ingredients
1
Amounts stated
All
Status
Restricted substance
Evidence summaries
1

Overview

Manufacturer information

GynSyn Labs MK677 liquid 30 ml (1ml 90mg) contains MK677 (Ibutamoren): 75 mg. Each pack holds 30 ml (liquid).

Ingredients & composition

Manufacturer information
IngredientAmount
MK677 (Ibutamoren)75 mg

Scientific background

Independent research

MK-677 (ibutamoren)

MK-677 (ibutamoren) is an orally active growth hormone secretagogue: it mimics the hormone ghrelin and stimulates the release of growth hormone and IGF-1. It is often grouped with SARMs but works through a different mechanism1.

Research evidence

Independent research

MK-677 (ibutamoren)

In a 12-month randomised trial in healthy older adults, MK-677 increased growth hormone secretion and fat-free mass and was generally well tolerated1.

In a phase IIb trial in older patients recovering from hip fracture, IGF-1 levels rose but most measures of physical function did not improve, and the authors concluded that MK-677 had an unfavourable safety profile in that population, including congestive heart failure in a limited number of patients2.

Evidence limitations

Independent research

No published study has tested this specific product; the research summarised here concerns the ingredient itself.

MK-677 (ibutamoren)

The trials were in older adults under medical supervision. There are no controlled studies in healthy young people or athletes. Analyses of products sold online as SARMs found that many did not contain the substance or amount stated on the label, and some contained other unapproved drugs3.

Safety & potential risks

Independent research

MK-677 (ibutamoren)

Reported effects in trials include increased appetite, fluid retention and raised blood glucose; heart failure occurred in a small number of frail older patients12.

Regulatory status

GIGACULT product information

Contains an investigational growth-hormone secretagogue. It is not authorised as a medicinal product or as food (including food supplements) in the EU and is on the WADA Prohibited List. No dosing information for human use is provided.

Regulation and sport

MK-677 (ibutamoren)

MK-677 is not an approved medicine and is not permitted in food or food supplements in the EU45. Growth hormone secretagogues are prohibited at all times by the World Anti-Doping Agency6.

Scientific references

  1. Nass R, Pezzoli SS, Oliveri MC, et al. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008;149:601-611. PubMed 18981485
  2. Adunsky A, Chandler J, Heyden N, et al. MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: a multicenter, randomized, placebo-controlled phase IIb study. Arch Gerontol Geriatr. 2011;53:183-189. PubMed 21067829
  3. Van Wagoner RM, Eichner A, Bhasin S, et al. Chemical composition and labeling of substances marketed as selective androgen receptor modulators and sold via the internet. JAMA. 2017;318:2004-2010. PubMed 29183075
  4. Directive 2001/83/EC on the Community code relating to medicinal products for human use. Official Journal of the European Union. Source
  5. Regulation (EU) 2015/2283 on novel foods. Official Journal of the European Union. Source
  6. World Anti-Doping Agency. The Prohibited List (current edition). Source

Sources checked against PubMed, Crossref or the official publisher on 2026-11-04. Manufacturer information is taken from the product's own data and has not been independently tested.

The product

GynSyn Labs MK677 liquid 30 ml (1ml 90mg)

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