Product guide · Restricted substance

Nucleon Nutrition TB-500 5 mg peptide

Peptide product from Nucleon Nutrition. This guide sets out what the manufacturer states about the composition of Nucleon Nutrition TB-500 5 mg peptide, what independent research says about its main ingredient, and the safety and regulatory points that apply. It contains substances that are not authorised as food or medicine in the EU. This guide is educational: it does not recommend use and gives no directions for use.

Educational guide · Sources checked 4 November 2026 · 5 references

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Named ingredients: 1
Amounts stated: None
Status: Restricted substance
Evidence summaries: 1

Overview

Manufacturer information

Nucleon Nutrition TB-500 5 mg peptide contains TB-500. The strength is given in the product title.

Ingredients & composition

Manufacturer information

Ingredient	Amount
TB-500	Not stated

The manufacturer does not state the amount of any ingredient. Without amounts, the research summarised in this guide cannot be related to this product's dose.

Scientific background

Independent research

TB-500 (thymosin β4 fragment)

TB-500 is marketed as a synthetic version or fragment of thymosin β4 (Tβ4), a naturally occurring protein involved in cell migration and tissue repair¹.

Research evidence

Independent research

TB-500 (thymosin β4 fragment)

Thymosin β4 accelerated dermal healing in animal models and in phase 2 trials in patients with pressure ulcers, venous stasis ulcers and epidermolysis bullosa wounds¹. Those trials used the full natural protein in clinical settings, not TB-500 products.

Evidence limitations

Independent research

This product does not state all ingredient amounts, so the doses used in research cannot be compared with what one serving provides.

No published study has tested this specific product; the research summarised here concerns the ingredient itself.

TB-500 (thymosin β4 fragment)

There are no published controlled human trials of TB-500 products for muscle or tendon injuries or performance. Reviewers describe a "gray market" of unapproved peptides sold directly to consumers outside regulatory oversight, with uncertain purity and safety².

Safety & potential risks

Independent research

TB-500 (thymosin β4 fragment)

Human safety data for TB-500 products are lacking².

Regulatory status

GIGACULT product information

Contains a peptide that is not authorised as food (including food supplements) or as a medicinal product in the EU. No dosing information for human use is provided.

Regulation and sport

TB-500 (thymosin β4 fragment)

TB-500 is not authorised as a medicine or as a food in the EU³⁴. The World Anti-Doping Agency prohibits non-approved substances and peptide hormones, growth factors and related substances at all times⁵.

Scientific references

Kleinman HK, Sosne G. Thymosin β4 promotes dermal healing. Vitam Horm. 2016;102:251-275. PubMed 27450738
Mendias CL, Awan TM. Safety and efficacy of approved and unapproved peptide therapies for musculoskeletal injuries and athletic performance. Sports Med. 2026;56:1921-1935. PubMed 41966639
Directive 2001/83/EC on the Community code relating to medicinal products for human use. Official Journal of the European Union. Source
Regulation (EU) 2015/2283 on novel foods. Official Journal of the European Union. Source
World Anti-Doping Agency. The Prohibited List (current edition). Source

Sources checked against PubMed, Crossref or the official publisher on 2026-11-04. Manufacturer information is taken from the product's own data and has not been independently tested.

The product