Product guide · Restricted substance
Renegade Pharma Beast in a bottle 90 caps
Prohormone product from Renegade, 90 capsules. This guide sets out what the manufacturer states about the composition of Renegade Pharma Beast in a bottle 90 caps, what independent research says about its main ingredients, and the safety and regulatory points that apply. It contains substances that are not authorised as food or medicine in the EU. This guide is educational: it does not recommend use and gives no directions for use.
Back to the product- Named ingredients
- 5
- Amounts stated
- None
- Status
- Restricted substance
- Evidence summaries
- 4
Overview
Manufacturer informationIngredients & composition
Manufacturer information| Ingredient | Amount |
|---|---|
| Epistane | Not stated |
| Halodrol | Not stated |
| AAKG (arginine alpha-ketoglutarate) | Not stated |
| Uva ursi (bearberry) | Not stated |
| Milk thistle | Not stated |
The manufacturer does not state the amount of any ingredient. Without amounts, the research summarised in this guide cannot be related to this product's dose.
Scientific background
Independent researchProhormones and designer anabolic steroids
Prohormones and "designer steroids" are synthetic anabolic-androgenic steroids, or precursors converted to them in the body, sold in supplement-style products. Examples include methasterone ("Superdrol"), methylepitiostanol ("Epistane") and trendione ("Trenavar").
L-arginine and AAKG
L-arginine is an amino acid used by the body to make nitric oxide. AAKG is arginine bound to alpha-ketoglutarate.
Uva ursi (bearberry leaf)
Uva ursi (bearberry) leaf contains arbutin, which is converted to hydroquinone, and is a traditional remedy for urinary tract complaints.
Milk thistle (silymarin)
Milk thistle (Silybum marianum) seeds contain silymarin, a mixture of flavonolignans studied for liver protection1.
Research evidence
Independent researchProhormones and designer anabolic steroids
No controlled trials support the safety of these products. Their muscle-building effect derives from anabolic-androgenic steroid activity, the same mechanism as controlled steroid drugs.
L-arginine and AAKG
A dose-response meta-analysis of randomised trials found that L-arginine lowered blood pressure in adults2. Evidence for improved exercise performance or "pump" is inconsistent; oral arginine is extensively broken down before reaching the circulation, which is why citrulline is often preferred3.
Uva ursi (bearberry leaf)
A risk assessment concluded that, under the recommended use conditions for herbal medicines, uva ursi leaf is a safe option for treating lower urinary tract infections4.
Milk thistle (silymarin)
A meta-analysis of randomised trials in people with liver injury reported improvements in some liver markers with silymarin5. These trials concern patients with liver disease, not healthy users.
Evidence limitations
Independent researchThis product does not state all ingredient amounts, so the doses used in research cannot be compared with what one serving provides.
The studies summarised in this guide examined single ingredients. No published study has tested this product or this combination of ingredients.
Prohormones and designer anabolic steroids
Products are often mislabelled or adulterated, so the actual steroid and dose are uncertain67.
L-arginine and AAKG
Studies vary in dose and population2.
Uva ursi (bearberry leaf)
Its use is short-term and medicinal; it is not studied as a daily supplement4.
Milk thistle (silymarin)
Trials vary widely in preparation, dose and patient group, and do not show that silymarin prevents liver damage from drugs or other substances5.
Safety & potential risks
Independent researchProhormones and designer anabolic steroids
Case reports describe drug-induced liver injury, including cholestasis, from prohormone and bodybuilding supplements containing anabolic-androgenic steroids678. Anabolic steroids also suppress natural testosterone production and adversely affect blood lipids and the heart.
L-arginine and AAKG
A risk assessment identified an observed safe level of 20 g a day9. Because it lowers blood pressure, people taking blood-pressure or erectile-dysfunction medication should ask a doctor first2.
Uva ursi (bearberry leaf)
Uva ursi should only be used short-term because of hydroquinone exposure, and not in pregnancy, breastfeeding or kidney disease4.
Milk thistle (silymarin)
Silymarin is generally well tolerated and has few drug interactions, but caution is advised with medicines that have a narrow therapeutic window; safety in pregnancy is not established1.
Regulatory status
Contains synthetic anabolic-androgenic steroid compounds or prohormones. These are not authorised as food (including food supplements) or as medicinal products in the EU and are on the WADA Prohibited List. No dosing information for human use is provided.
Prohormones and designer anabolic steroids
Anabolic-androgenic steroids are medicinal substances and are not permitted in food or food supplements in the EU1011. Anabolic agents are prohibited at all times by the World Anti-Doping Agency12.
L-arginine and AAKG
No health claim for this ingredient is authorised in the EU13; botanical ingredients are sold under national food-supplement rules14.
Scientific references
- Soleimani V, Delghandi PS, Moallem SA, et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: an updated review. Phytother Res. 2019;33:1627-1638. PubMed 31069872
- Shiraseb F, Asbaghi O, Bagheri R, et al. Effect of L-arginine supplementation on blood pressure in adults: a systematic review and dose-response meta-analysis of randomized clinical trials. Adv Nutr. 2022;13:1226-1242. PubMed 34967840
- Gonzalez AM, Trexler ET. Effects of citrulline supplementation on exercise performance in humans: a review of the current literature. J Strength Cond Res. 2020;34:1480-1495. PubMed 31977835
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos uva-ursi folium herbal preparations. Int J Toxicol. 2013;32:442-453. PubMed 24296864
- Shahsavari K, Ardekani SS, Ardekani MRS, et al. Are alterations needed in Silybum marianum (silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury. BMC Complement Med Ther. 2025;25:134. PubMed 40221681
- Magee CD, Witte S, Kwok RM, Deuster PA. Mission compromised? Drug-induced liver injury from prohormone supplements containing anabolic-androgenic steroids in two deployed U.S. service members. Mil Med. 2016;181:e1169-e1171. PubMed 27612377
- Matusak M, Aljabban J, Wirtz M, et al. Cholestasis linked to bodybuilding supplements: exploring the risks of contamination. Case Reports Hepatol. 2024;2024:5112461. PubMed 38826497
- Nash E, Nicoll A, Batt N, et al. Drug-induced liver injury from selective androgen receptor modulators, anabolic-androgenic steroids and bodybuilding supplements in Australia. Aliment Pharmacol Ther. 2024;59:953-961. PubMed 38372012
- Shao A, Hathcock JN. Risk assessment for the amino acids taurine, L-glutamine and L-arginine. Regul Toxicol Pharmacol. 2008;50:376-399. PubMed 18325648
- Directive 2001/83/EC on the Community code relating to medicinal products for human use. Official Journal of the European Union. Source
- Regulation (EU) 2015/2283 on novel foods. Official Journal of the European Union. Source
- World Anti-Doping Agency. The Prohibited List (current edition). Source
- Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods. Official Journal of the European Union. Source
- Directive 2002/46/EC on the approximation of the laws of the Member States relating to food supplements. Official Journal of the European Union. Source
Sources checked against PubMed, Crossref or the official publisher on 2026-11-04. Manufacturer information is taken from the product's own data and has not been independently tested.

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Renegade Pharma Beast in a bottle 90 caps
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