Product guide · Under compliance review
Smart Brothers NAD+ 60 caps
Specialised product from Smart Brothers, 60 capsules. This guide sets out what the manufacturer states about the composition of Smart Brothers NAD+ 60 caps, what independent research says about its main ingredient, and the safety and regulatory points that apply. Its regulatory status is under compliance review. This guide is educational and does not recommend use.
Back to the product- Named ingredients
- 1
- Amounts stated
- None
- Status
- Under compliance review
- Evidence summaries
- 2
Overview
Manufacturer informationSmart Brothers NAD+ 60 caps contains NAD+ (nicotinamide adenine dinucleotide). Each pack holds 60 capsules. The strength is not stated in the product data.
Ingredients & composition
Manufacturer information| Ingredient | Amount |
|---|---|
| NAD+ (nicotinamide adenine dinucleotide) | Not stated |
The manufacturer does not state the amount of any ingredient. Without amounts, the research summarised in this guide cannot be related to this product's dose.
Scientific background
Independent researchNiacin (vitamin B3: nicotinic acid, niacinamide)
Niacin (vitamin B3) is used to make the coenzymes NAD and NADP, which are central to energy metabolism. It exists as nicotinic acid and nicotinamide (niacinamide)1.
NAD+ and NMN
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme in energy metabolism whose levels decline with age. NMN (nicotinamide mononucleotide) and nicotinamide riboside are precursors that the body converts to NAD+.
Research evidence
Independent researchNiacin (vitamin B3: nicotinic acid, niacinamide)
Authorised EU claims include that niacin contributes to normal energy-yielding metabolism, the reduction of tiredness and fatigue, and the maintenance of normal skin2.
NAD+ and NMN
A 2026 systematic review of trials of oral NMN found good short-term tolerability but no clear broad metabolic benefits, with preliminary signals on blood pressure and insulin resistance3. Evidence for injected or nasal NAD+ products is very limited.
Evidence limitations
Independent researchThis product does not state all ingredient amounts, so the doses used in research cannot be compared with what one serving provides.
The studies summarised in this guide examined single ingredients. No published study has tested this product or this combination of ingredients.
Niacin (vitamin B3: nicotinic acid, niacinamide)
Benefits of intakes well above needs are not established in people who are not deficient.
NAD+ and NMN
Trials are short and small; larger, longer trials are needed to confirm efficacy and long-term safety3.
Safety & potential risks
Independent researchNiacin (vitamin B3: nicotinic acid, niacinamide)
The EU Scientific Committee on Food set separate upper levels: 10 mg a day for nicotinic acid, which causes flushing, and 900 mg a day for nicotinamide4. "Flush-free" products use nicotinamide or inositol hexanicotinate.
NAD+ and NMN
Short-term oral NMN was well tolerated in trials3. Injectable NAD+ products are not quality-controlled medicines.
Regulatory status
Flagged for compliance review: this product is listed as a food supplement in our catalogue, but its EU status (food supplement, novel food or medicinal product) has not been verified. No benefits or health claims are made.
Scientific references
- EFSA NDA Panel. Scientific Opinion on Dietary Reference Values for niacin. EFSA Journal. 2014;12:3759. DOI 10.2903/j.efsa.2014.3759
- Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods. Official Journal of the European Union. Source
- Yang W, Huang J, Tang Z, et al. Safety and metabolism-related outcomes of oral nicotinamide mononucleotide supplementation in adults: a systematic review and meta-analysis. Nutrients. 2026;18. PubMed 42514320
- Scientific Committee on Food / EFSA. Tolerable Upper Intake Levels for Vitamins and Minerals. European Food Safety Authority; 2006. Source
- Directive 2002/46/EC on the approximation of the laws of the Member States relating to food supplements. Official Journal of the European Union. Source
- Regulation (EU) 2015/2283 on novel foods. Official Journal of the European Union. Source
- Directive 2001/83/EC on the Community code relating to medicinal products for human use. Official Journal of the European Union. Source
Sources checked against PubMed, Crossref or the official publisher on 2026-11-04. Manufacturer information is taken from the product's own data and has not been independently tested.
The product
Smart Brothers NAD+ 60 caps
€39,90 · Sold out